33rd Congress of the Eur Dial Transplant Assoc -- June, 1996

Selected Abstracts


This review was prepared by Drs. Carlo Basile, Bruno Cianciaruso, Loreto Gesualdo, and Carmine Zoccali. Dr. Carmine Zoccali acted as coordinator.

Hypertension


Kidney in hypertension

h Diuretic efficacy of low dose atrial natriuretic peptide (ANF) in CRF
h The role of chemokines and cytokines in the initiation and progression of hypertensive nephrosclerosis

Endocrine hypertension

h High concentrations of interleukin 1 beta in patients with essential hypertension before any drug therapy: a pilot preliminary study

Women

h Pre-eclampsia: A pathogenetic role for nitric oxide synthase


Dialysis, Chronic Renal Failure


Dialyzers

d Thermal energy flow and body temperature as a parameter of biocompatibility during hemodialysis in ESRD
d Randomized trial on the effect of different membranes and dialysis technologies

Complications (acute)

d Critical role of the extracorporeal blood temperature in the hemodynamic response during hemofiltration

Cardiovascular/Hypertension

d Endothelin-1 generation and endothelin-1 mediated basal vascular tone is decreased in chronic renal failure
d Endothelin-1 and reflex circulatory control in dialysis patients

GI/Liver, Hepatitis

d Intestinal absorptive function and plasma levels of anorexigenic substances in peritoneal dialysis patients. Their relationship with malnutrition

Joint disease, beta-2 microglobulin

d A new approach to the detection of dialysis related amyloidosis with 99m Tc aprotinin
d Beta-2-microglobulin modified with advanced glycation end products enhances osteoclast-induced bone resorption: Role in the pathogenesis of dialysis-related amyloidosis
d Selective extracorporeal removal of beta-2-microglobulin with adsorbent column in dialysis related amyloidosis: multicenter study
d 3-deoxyglucosone accumulating in uremic serum modified beta-2- microglobulin with age as observed in dialysis related amyloidosis

Bone disease/aluminum

d Renagel-TM, a calcium and alluminium-free phosphate binder lowers serum phosphorus in haemodialysis patients
d Bone strontium levels are increased in dialysis patients with osteomalacia
d Nodular parathyroid hyperplasia is refractory to medical treatments

Infections (other than hepatitis, peritonitis)

d Monocyte apoptosis in chronic hemodialysis patients

Outcomes (Morbidity, Mortality)

d Are inflammatory markers predictive of mortality in hemodialysis?

Rehabilitation, exercise

d Effect of exercise training on muscle atrophy in hemodialysis patients

Complications of PD

d Therapeutic effect of newly-developed antifibrotic agent pirfenidon compbined with home parenteral nutrition on sclerosing encapsulated peritonitis

Progression

d ACE and angiotensin genotype influence progression of primary renal disease


Clinical Nephrology


Embolic disease

c A growing cause of iatrogenic renal failure: cholesterol crystal embolisation. A series of 50 patients at one institution

Hereditary polycystic disease

c Novel mutation and polymorphism in the PKD1 gene of a polycystic kidney disease family

Pathogenesis, complications, RVT

c Proteinuria induces apoptosis in cultured tubular cells
c Oral sodium bicarbonate suppresses renal tubular peptide catabolism, ammoniagenesis and reduces renal tubular injury in renal patients

Mechanisms of renal injury

c Tubular MCP-1 production, a mechanism for proteinuria-induced interstitial inflammation
c Monocyte chemotactic peptide-1 (MCP-1) expression in IgA nephropathy: a pathogenetic role in interstitital monocytes recruitment
c alpha-smooth muscle actin and PDGF-beta receptor expression in human IgA nephropathy: potential markers of tubulo-interstitial cell activation
c TGF-beta and endothelin-1 expression in IgA glomerulonephritis correlates with the progression of renal damage
c Angiotensin II triggers monocyte chemoattractant protein-1 MCP- 1 transforming growth factor (TGF-B1) and matrix protein gene expresion in mesangal cells and interstitial renal fibroblast

Cryoglobylonemia not due to hepatitis

c Cryoglobulinemic glomerulonephritis: in situ hybridization for HCV in renal tissue

Hereditary hematuria/proteinuria

c Familial occurence of lipoprotein glomerulopathy

Membranous GN

c Actuarial survival and associated malignancy in membranous nephropathy: a registry linkage study

Transplantation

c Detection of hepatitis C virus RNA genome in liver biopsies of renal transplants


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