50th Annual Fall Conference AHA Council for High Blood --Sep: 1996 Pressure Research

Selected Abstracts




Hypertension


Endothelium, Nitric Oxide

h Endothelial cells contain a novel angiotensin (1-7) binding site

Genetics

h Association of angiotensin gene haplotype to the serum angiotensinogen concentration and blood pressure in blacks and whites
h Angiotensin converting enzyme gene polymorphisms, plasma levels, and left ventricular size in twins
h Losartan versus gene therapy: Chronic control of high blood pressure in spontaneously hypertensive rats

Hormonal aberrations

h Essential hypertension is associated with low urinary levels of angiotensin (1-7)
h Angiotensin (1-7) potentiates vasodilation of bradykinin in canine coronary artery by local release of nitric oxide

Vascular pathology

h Intima-media thickness of carotid artery in patients with hypertensive heart disease and hypertensive cardiomyopathy

Salt (sodium, chloride) sensitivity

h Nocturnal blood pressure decline is attenuated by NaCl loading in salt-sensitive patients with essential hypertension

Hypokalemia

h Bartter's syndrome is caused by mtations in the Na-K-2Cl cotransporter


Dialysis, Chronic Renal Failure


Cardiovascular/Hypertension

d Functional expression of CD40 on human coronary vascular smooth muscle cells


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