Koda Y, Miyazaki S, Yamazaki H, et al.
Relation of the dialyzer membrane used with the progress of amyloidosis or with patient mortality
Japanese Soc Nephrol
J Japanese Soc Nephrol (Nov) 37:(suppl)85 1995

The authors employed the Cox proportional hazard model to assess the impact of the dialyzer membrane material on the progress of amyloidosis and mortality. The end point was time to operation for carpal tunnel syndrome (using consistent operative criteria) and the time of death. A total of 819 hemodialysis patients from Shinrakuen Hospital were studied, with follow-up ranging up to 28 years.

The risk of surgery for carpal tunnel syndrome among patients with whom synthetic membranes (i. e., polysulfone, polyacrylonitrile and polymethylmetacrylate) was found to be 0.50 times that for patients in whom a cuprophane membrane was employed. Furthermore, the risk of death among patients in whom synthetic membranes were used proved to be 0.61 times that of the patients treated with cuprophane membranes. (T. Shinzato)

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Japanese Soc Nephrol
CRF: Problem Areas : Outcomes (Morbidity, Mortality)
CRF by organ system : Joint disease, beta-2 microglobulin