Quarello F, Piccoli G
Mortality and arterial pressure in dialysis patients
Clin Hyp Nephrol (Calab)
(Sep) : 1995
The relationship between arterial hypertension and mortality in dialysis
patients was analyzed from the Piedmont Registry of Dialysis and
Transplantation
files. The main cause of death among 1,945 dialysis patients (1981-1993) was
cardiovascular (49%). Prevalence of pre-dialysis hypertension (BP > 140/90
mm Hg), recorded at first updating (on average 180 days after start of
treatment)
ranged from 32% (males, aged 0-19 years) to 100% (patients aged 20-29
years),
averaging 77% in the other age groups.
Cumulative survival at twelve years in
dialysis patients in the age group 45-64 years without risk conditions,
according to the Third Joint National Committee criteria, was significantly
lower (p=0.0003) in systolic and moderate hypertensive than in normotensive,
borderline and mild hypertensive patients. In the same group of patients,
survival of those who modified their blood pressure from introduction to
maintenance phase becoming normotensive was similar to that of patients
persistently normotensive and significantly better (p=0.0091) than that of
patients who remained hypertensive. In subjects older than 65 years or with
high risk conditions no correlation was found between arterial pressure and
survival.
(authors)
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CRF: Problem Areas :
Outcomes (Morbidity, Mortality)
CRF by organ system :
Cardiovascular/Hypertension