Pizzarelli F, Morales MA, Ferdeghini EM, Dattolo P, Maggiore Q
Assessment of myocardial structure of dialysis patients

Clin Hyp Nephrol (Calab) (Sep) : 1995

To evaluate whether uremic myocardium shows a peculiar ultrasonic pattern, we studied 40 HD patients and 17 non uremic hypertensives with comparable left ventricular mass and septal hypertrophy. The distribution of gray levels within a region of interest in the intraventricular septum was analyzed off-line by an array processor based computer.

Compared with hypertensives, HD patients showed a greater myocardial echogenecity (p<01) and a reduced homogeneity of distribution of gray levels (p<01). By stepwise regression analysis, CaxP product, degree of acidosis, HD age and mean arterial pressure accounted for 55% of the inhomogeneity. HD patients were divided according to presence (MAC+, 20 patients) or absence (MAC-, 17 patients) of mitral annular calcification. (MAC + patients showed a more refractile and less homogeneous echo pattern than MAC- patients (p<01). (authors)

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CRF by organ system : Cardiovascular/Hypertension