Schwartz JE, Grossman S, Warren K, Pickering TG
The temporal stability (correlation) of mean awake and sleep ambulatory blood pressure
12th Annual ASH Meeting
Am J Hypertens (Apr) 10:213A 1997

The short and long term reproducibility of ambulatory blood pressure is quite good when the studies are performed under standardized conditions. This fact has allowed the use of ambulatory blood pressure monitoring in clinical trials with a reduction of the sample size typically required using office blood pressure. Traditionally the reproducibility has been studied using correlation coefficients and Bland-Altman plots. In the current study, the authors used a recently developed method of maximum likelihood (ML) to eliminate the variability associated with sampling.

The study population consisted of 223 participants of the Work Site BP study who wore an ambulatory monitor twice some 2-4 years apart. The authors found that the ML method gave higher correlation coefficients than the traditional coefficient. The authors concluded that traditional methods underestimate the correlation of ambulatory blood pressure.

Comment: These data enhance our belief that multiple readings of blood pressure are more likely to be reproducible than single or office based readings. Such good reproducibility will continue to allow us to detect small changes in blood pressure. (George Mansoor, M.D., University of Connecticut)

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12th Annual ASH Meeting
H: Exam and lab tests : Ambulatory monitoring

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