Hymes LC, Scaglia F, Maki A Jr, Vogler LB
Minimal change nephrotic syndrome resulting from
Ehrlichiosis
1996 Spring Clinical Nephrology Meetings
Am J Kidney Dis
(Apr) 26:A7 1996
Hymes et al present a case of minimal change disease in a 16 year old
male who was discovered to have elevated IgG titer to Ehrlichia
canis which fell significantly within two weeks. The patient was
treated with both doxycycline and daily corticosteroids and went into
remission leading the authors to suggest that ehrlichiosis may be an
unrecognized cause of minimal change disease.
Comment: A much better argument could have been made for
Ehrlichia as a cause of minimal change disease had the patient
been treated with doxycycline alone. It will be interesting to see
if this report stimulates other case reports of this rickettsial
organism associated with glomerular disease.
(N. Kevin Krane, M.D., Tulane University)
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1996 Spring Clinical Nephrology Meetings
Proteinuria/Hematuria :
Minimal change disease