Fong EP, Foote EF, Suh DC, Steward CA, Pickard MV, Sherman RA
Cost minimization of erythropoietin at an outpatient hemodialysis center
1996 Spring Clinical Nephrology Meetings
Am J Kidney Dis (Apr) 26:A6 1996

This study documented the efficacy of methods designed to save EPO costs. EPO was obtained in 10,000 unit single dose vials. However, use of EPO overfill (1-2,000 units per vial) was maximized by a system of nursing education about EPO costs, which included refrigeration of partially used vials, and use on the subsequent shift. Additionally, use of the MedSaver syringe, which utilizes a permanently attached needle, and which minimizes the dead space in the syringe after complete depression of the plunger, was evaluated.

Prior to these measured, about 9,800 unit of EPO were recoverd from each vial. After nursing education, this increased to 10,900 units per vial, and use of the MedSaver syringe plus nursing education resulted in obtaining 11,780 units from each "10,000 Unit" vial. The total cost savings of these measures was computed to be $145,000 dollars per year!!

Comment: The benefits of this approach are obvious. Kudos to Dr. Sherman's group for undertaking a very practical and useful research project. (John T. Daugirdas, M.D., University of Illinois at Chicago)

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1996 Spring Clinical Nephrology Meetings
CRF by problem area : Anemia/Erythropoietin/Iron