Nakazawa R, Gejyo F, Arakawa M, Suzuki M, Hara S, Kawaguchi
Y.
Selective extracorporeal removal of beta-2-microglobulin with
adsorbent column in dialysis related amyloidosis: multicenter
study
33rd Congress of the Eur Dial Transplant Assoc
Nephrol Dial Transplant
(Jun) 11:A239 1996
Presently there is no efficacious treatment of Beta 2 microglobulin
amyloidosis in HD patients (renal transplantation apart). The authors
tested the efficacy of a direct hemoperfusion technique with a column
(BM 01) which effectively binds circulating beta 2 microglobulin. 24
patients with dialysis related amyloidosis participated in the study.
The column was connected in series with a polysulphone filter and
patients were randomized to receive either HD alone or HD + BM 01
hemoperfusion.
Beta 2 microglobulin showed a 40% fall in
patients treated with the BM 01 column. Interestingly these patients
showed also an improvement in daily living activities as well as in
joint pain and mobility. This new technique opens a new perspective
for delaying the progression of dialysis amyloidosis. (Carmine
Zoccali, M.D., Reggio Calabria, Italy).
To go back use the BACK button on your browser.
Otherwise click on the desired link to this article below:
33rd Congress of the Eur Dial Transplant Assoc
CRF by organ system :
Joint disease, beta-2 microglobulin
other extracorporeal therapies :
New dialysis methods, hemodiafiltration