Kuhlman U, May M, Schoenemann H, Kramer M, Lange H
Thermal energy flow and body temperature as a parameter of biocompatibility during hemodialysis in ESRD
33rd Congress of the Eur Dial Transplant Assoc
Nephrol Dial Transplant (Jun) 11:A239 1996

Inflammation-like reactions are induced by dialysis membranes and a rise in heat production and in blood temperature is an expected effect of bio-incompatible membranes.

The hypothesis was tested in eleven uremic patients. Patients were dialyzed in a random way with four different dialyzers (cuprophane Vs polysulfone - 1.3 Vs 1.8 m2). Thermal energy flow of the dialyzer and blood temperature were measured continuously by the Blood Temperature Monitor (BTM, Fresenius AG). At equivalent thermal energy flows, blood temperature increased significantly (p < 0.05) in cuprophan HD in comparison with Polysulphone HD, independently of membrane surface area.

Comment: Changes in blood temperature during dialysis may represent an additional, simple marker of membrane biocompatibility (Carlo Basile, M.D., Taranta, Italy).

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33rd Congress of the Eur Dial Transplant Assoc
Basic hemodialysis : Dialyzers
Basic hemodialysis : Complications (acute)