Kouidi E, Albani M, Buiga-Tziampiri O, Deligiannis A,
Tourkantonis A
Effect of exercise training on muscle atrophy in hemodialysis
patients
33rd Congress of the Eur Dial Transplant Assoc
Nephrol Dial Transplant
(Jun) 11:A175 1996
Inactivity seems to be one of the main causes of muscle wasting and
weakness in HD patients. This study examines the effects of physical
training on muscle histology in 7 hemodialysis patients who
participated in a 6-month rehabilitation program (3 weekly sessions of
exercise training). Open muscle biopsies, muscle strength as well as
maximum oxygen consumption and motor conduction velocity (MCV) were
obtained before and after the training program.
At the end of the rehabilitation program the mean muscle
fiber area increased by 29 % (p<0.05) (type I fibers:+26%, type II
fibers: +24%), maximum oxygen consumption by 48 % (p<0.05), and
muscle strength by 42 % (p<0.05) and MCV by 10% (p<0.05). These data
give further strength to the evidence accumulated so far that
physical rehabilitation can be effectively used to increase the work
capacity of hemodialysis patients.
Comment: A weak point of this interesting study is that
factors other than exercise training "per se" (amount of dialysis
delivered, vitamin D supplements, protein and caloric intake) could
have influenced the results (Bruno Cianciaruso, M.D., University
of Naples, Italy).
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33rd Congress of the Eur Dial Transplant Assoc