Danelakos GN, Elisaf M, Papagalanis N, Zallas CT, Baraiktari
E, Siamopoulos KC
High concentrations of interleukin 1 beta in patients with
essential hypertension before any drug therapy: a pilot
preliminary study
33rd Congress of the Eur Dial Transplant Assoc
Nephrol Dial Transplant
(Jun) 11:A15 1996
Immunological alterations have been reported in animal models of
hypertension as well as in human hypertension. In this study the
plasma concentrations of IL-1 beta and IL-2 were measured in 114
untreated essential hypertensives and in 20 healthy subjects. No
alteration was found in plasma IL-2. However, the plasma concentration
of IL-1 beta was 9 times higher in essential hypertensives (503
pg/ml) than in healthy subjects (58 pg/ml).
Comment: Undoubtely these data are of interest. However
the magnitude of the difference in plasma IL1-Beta between
hypertensive and normotensive subjects raises a credibility problem.
Were the lab results triple checked? (Carmine Zoccali, M.D.,
Reggio Calabria, Italy).
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33rd Congress of the Eur Dial Transplant Assoc
H: Special problems :
Endocrine hypertension