Belenfant X, Rossert J, d'Auzac C, Caudwell W, Jacquot C
A growing cause of iatrogenic renal failure: cholesterol crystal
embolisation. A series of 50 patients at one institution
33rd Congress of the Eur Dial Transplant Assoc
Nephrol Dial Transplant
(Jun) 11:A85 1996
Cholesterol embolization is considered a rare cause of renal failure. This
is the largest series
presented so far. Patients with such disease were
old ( 70 years) and males (M/F=9/1). In the
great majority (96%)
embolization was caused by angiographic procedures, cardiovascular surgery
or
anticoagulation. Skin signs of widespread embolization (livedo
reticularis) were present in as
much as 85% of cases and a high eosinophil
count in 50%. Renal failure proved to be irreversible
in 40% of cases and
haemodialysis was required in 61%. Two years mortality in these cases
was
47%.
Comment:
This series further confirm that cholesterol embolization is much less rare
than previously thought.
This complication probably constitutes one of the
main causes of acute renal failure in the elderly
and entails a high
morbidity and mortality (Carmine Zoccali, M.D., Reggio Calabria,
Italy).
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33rd Congress of the Eur Dial Transplant Assoc
ARF etiology :
Embolic disease